Build, runes, synergies, counters, lore. Cassiopeia is a mid-lane mage in “League of Legends” known for her sustained damage output and crowd control abilities.

General Description

Cassiopeia is a mage who excels at dealing sustained damage to enemies with her poison abilities. She also has the ability to slow and stun enemies with her ultimate, which can help her team secure kills or escape dangerous situations.

Cassiopeia Build

Cassiopeia benefits from items that increase her ability power and mana sustain, such as Luden’s Echo or Seraph’s Embrace. She can also opt for items that provide additional survivability, such as Zhonya’s Hourglass or Banshee’s Veil.

Cassiopeia Runes

In the rune tree, Cassiopeia typically runs either Conqueror or Dark Harvest for more damage output. She can also choose to run Inspiration secondary for more sustain.

Cassiopeia Synergies

Cassiopeia works well with allies who can provide additional crowd control or engage, such as Sejuani or Malphite. She also pairs well with allies who can protect her and peel for her, such as Lulu or Janna.


Cassiopeia can struggle against enemies who can gap-close and burst her down quickly, such as Zed or LeBlanc. To counter her, it is important to stay out of her poison range and to focus on disrupting her sustained damage.


Cassiopeia is a member of the wealthy and powerful Du Couteau family in the city-state of Noxus. She was transformed into a half-snake creature by dark magic and now seeks a cure for her curse, while also using her powers to further her family’s goals.


Keywords: Cassiopeia, mid-lane mage, League of Legends, sustained damage, crowd control, poison, slow, stun, ultimate, ability power, mana sustain, Luden’s Echo, Seraph’s Embrace, Zhonya’s Hourglass, Banshee’s Veil, Conqueror, Dark Harvest, Inspiration, crowd control, engage, Sejuani, Malphite, protect, peel, Lulu, Janna, gap-close, burst, Zed, LeBlanc, Du Couteau, Noxus, half-snake, curse, dark magic, family goals.


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